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From:	herman (71.190.78.198)
Subject:	B12 Supplement Chewing Study
Date:	May 6, 2009 at 9:37 am PST

Hi Jeff,

From the research link you provided about B12, is an excerpt which refers to a study where increased levels of b12 where achieved by chewing tablets. Your thoughts would be appreciated. Thanks.

Best,

Herman

ref: http://www.veganhealth.org/b12/vegansources#CHEW

Chew or Dissolve Supplements Under the Tongue

Crane et al.6 (1994, USA) noted that tablets of one vitamin company dissolved slowly in water and acid. They then conducted a study to see if vegan patients who had not responded to oral B12 (described below) tablets swallowed whole could improve their B12 response by chewing the tablets. 7 people chewed the tablets of 100 µg (once a week for 6 weeks) and their average serum B12 levels went from 116 to 291. Of the 9 who didn't chew, theirs increased from 123 to only 139. (However, a 100 µg dose once a week is not a lot of B12. The more surprising result of this experiment was the large increase in the serum B12 of the 7 people who chewed the tablets, not the small increase of those who did not chew.)

7 of these 9 then chewed 500 µg/day for 10 days and their levels rose to normal with a final average of 524 ± 235. Three participants could not raise their levels orally and required B12 injections to maintain serum B12 above 300.

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