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From: Jeff Novick, MS, RD, LD, LN (novick.vegsource.com)
Subject:         Re: VEGSOURCE TALK QUESTION (Second article)
Date: August 10, 2007 at 8:29 am PST

In Reply to: Re: VEGSOURCE TALK QUESTION posted by Stan B. on August 10, 2007 at 8:02 am:

this study was done with cocount oil as the fat.

BTW, if you want to design a diet that includes tropical oils, or
foods high in troical fats, i have no porblem with that. Just keep
your total saturated fat below 7% and opitmally below 5%.

In Health
Jeff

Even One High-In-Saturated-Fat Meal Fouls Up Your System

New research found that even one meal rich in saturated fat could
mess up the ability of “good” HDL cholesterol to protect against
damage to arteries.*

In the study, scientists at the Heart Research Institute in Sydney,
Australia fed a slice of carrot cake and a milkshake to 14 healthy,
normal-weight men and women, ages 18 to 40. The following
month, the subjects came back for another cake-and-shake meal.
Coconut oil – 90% saturated fat

Both meals were the same in their amounts of calories and total fat
but very different in the type of fat they contained. One meal was
made with coconut oil, which is 90% saturated fat. The other
contained safflower oil, which is predominately polyunsaturated
fat.

The immediate effect on the subjects’ arteries was very different,
too. Three and six hours after each meal, the scientists measured
blood flow and assessed how well HDL was protecting arteries from
inflammation. What they found is enough to make us put those
burgers and shakes down forever.

Compared to the polyunsaturated fat meal, the saturated fat meal
essentially turned “good” HDL cholesterol into “bad” HDL
cholesterol particles.

Let’s back up here a bit and explain HDL’s role. HDL is supposed
to be anti-inflammatory, that is, it’s supposed to inhibit the
proliferation of molecules that promote inflammation and cause
other molecules to stick to the artery wall, which can destabilize
atherosclerotic plaques, triggering plaque rupture and clot
formation. These molecules also thicken the blood and slow its
flow through the arteries, like congealed fat in liquid flowing
through kitchen pipes.

Sludge

After the saturated-fat-rich cake and shake, the scientists noted
that the subjects’ HDL particles were accompanied by high levels of
these damaging molecules. Moreover, blood flow in the forearms
of the subjects three and six hours after the saturated fat meal had
slowed considerably compared to blood flow after the non-
saturated-fat meal.

“What this new research shows is that inflammation and damage to
arteries happen soon after every meal high in saturated fat,”

“In effect, diets high in saturated fat alter the HDL particles,
changing them from so-called ‘good’ cholesterol into ‘bad’
cholesterol. Instead of being anti-inflammatory, they become pro-
inflammatory.”

Remnant chylomicrons

And HDL isn’t the only thing affected, notes Dr. Kenney. “Right
after a high-fat meal, whether saturated or unsaturated, there’s
increased production of remnant chylomicron particles. These
particles get into the artery wall and appear at least as artery
damaging as LDL ‘bad’ cholesterol.”
Clotting Factor VII

There is also an increase in Clotting Factor VII after each high-fat
meal, research has found. ** Elevated levels of Clotting Factor VII
increase the danger of plaque rupture, which increases the risk of a
fatal heart attack.

Ultimately, what these studies tell us is that taking care of our
arteries involves a lot more than just swallowing a statin drug to
lower LDL ‘bad’ cholesterol. Sure, getting LDL levels down to 100
and below is wonderful. But if you’re still eating cheese, red meat,
cookies, and other foods rich in saturated and trans fatty acids,
your arteries are still going to suffer.

Statins

“This is likely part of the reason why most people who take statin
drugs to lower their LDL cholesterol levels still have arteries that
get progressively more clogged up over time,” explains Dr. Kenney.
“Statin drugs do little to alter the production of pro-atherosclerotic
and pro-inflammatory HDLs and chylomicron remnants. Nor do
they lower the pro-clotting effects of Clotting Factor VII, which are
elevated after every high-fat meal.”

Yes, statin drugs may help speed repairs to damaged arteries, “but
it is becoming increasingly clear that relying on drugs alone is
likely to produce disappointing results,” notes Dr. Kenney. “For
many people, drugs plus diet are necessary.”

What has been scientifically documented to heal arteries and
reverse atherosclerosis are lifestyle changes involving regular
exercise and a lower-fat, vegetarian (or near) vegetarian diet Like
a good contractor for the remodeling of your house, a healthy
lifestyle takes care of all the variables needed to refurbish your
arteries. “Your arteries,” sums up Dr. Kenney, “get the complete
makeover they so desperately need.”

* Journal of the American College of Cardiology, 2006; 48: 715.
** American Journal of Clinical Nutrition, 1998; 67: 542S.

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