Follow Ups | Post Followup | Back to Discussion Board | VegSource
See spam or
inappropriate posts?
Please let us know.

From: TSS ()
Subject: Health officials investigate unusual incidence of Creutzfeldt-Jakob Disease TWIN FALLS, Idaho -- Five southern Idaho women
Date: July 29, 2005 at 7:52 am PST

----- Original Message -----
From: "Terry S. Singeltary Sr."
Sent: Friday, July 29, 2005 9:01 AM
Subject: Health officials investigate unusual incidence of Creutzfeldt-Jakob Disease

##################### Bovine Spongiform Encephalopathy #####################

Health officials investigate unusual incidence of CJD USA
Fri Jul 29, 2005 08:47

Friday, July 29, 2005 · Last updated 12:39 a.m. PT

Health officials investigate unusual incidence of Creutzfeldt-Jakob Disease


TWIN FALLS, Idaho -- Five southern Idaho women - four of whom have already died - have been diagnosed with Creutzfeldt-Jakob Disease since January, health officials say.

None of the cases appeared to be the variant type of the fatal disease, which is usually linked to mad cow disease.

Instead, health officials said, the women may have all developed the sporadic form of CJD, where the disease appears even though the person has no known risk factors.

The women - four in Twin Falls County, one in nearby Minidoka County - were all between the ages of 60 and 83.

"We do not think that there is any reason for the community to be alarmed about these cases," said Cheryle Becker, an epidemiologist at South Central District Health. "In our investigation so far, we do not see any common source of contagion between the women. We don't think there is any reason for people to change their eating, drinking or living habits. We will continue to investigate and inform the public of what we find."

Still, the number of cases in one small region is unusually high. Normally the disease infects only one out of every million people worldwide. In Idaho, there are normally about three cases of Creutzfeldt-Jakob Disease a year, according to the district health office. In recent years the entire United States has reported fewer than 300 cases annually, according to the Centers for Disease Control and Prevention.

The fatal, neurodegenerative disease causes normal brain proteins to fold, leading to brain damage. Symptoms include dementia and lack of coordination; most people die within one year of onset.

Laboratory tests that investigators hope will provide more clues are pending on tissue from two of the women.

"We need to find out if there's some situation that needs our attention," Becker said. "This may be five cases of sporadic CJD that just happened to occur in the same period of time."

The average age of people with the sporadic form of the disease is 68. The variant form usually affects younger people, with an average age of 28, according to the CDC.

In 2002, one case of variant CJD was diagnosed in a Florida resident who had lived in the United Kingdom.

IN light of Asante/Collinge et al findings that BSE transmission to the
129-methionine genotype can lead to an alternate phenotype that is
indistinguishable from type 2 PrPSc, the commonest _sporadic_ CJD;

-------- Original Message -------- Subject: re-BSE prions propagate as

either variant CJD-like or sporadic CJD Date: Thu, 28 Nov 2002 10:23:43

-0000 From: "Asante, Emmanuel A" To:

Dear Terry,

I have been asked by Professor Collinge to respond to your request. I am

a Senior Scientist in the MRC Prion Unit and the lead author on the

paper. I have attached a pdf copy of the paper for your attention. Thank

you for your interest in the paper.

In respect of your first question, the simple answer is, yes. As you

will find in the paper, we have managed to associate the alternate

phenotype to type 2 PrPSc, the commonest sporadic CJD.

It is too early to be able to claim any further sub-classification in

respect of Heidenhain variant CJD or Vicky Rimmer's version. It will

take further studies, which are on-going, to establish if there are

sub-types to our initial finding which we are now reporting. The main

point of the paper is that, as well as leading to the expected new

variant CJD phenotype, BSE transmission to the 129-methionine genotype

can lead to an alternate phenotype which is indistinguishable from type

2 PrPSc.

I hope reading the paper will enlighten you more on the subject. If I

can be of any further assistance please to not hesitate to ask. Best wishes.

Emmanuel Asante

<> ____________________________________

Dr. Emmanuel A Asante MRC Prion Unit & Neurogenetics Dept. Imperial

College School of Medicine (St. Mary's) Norfolk Place, LONDON W2 1PG

Tel: +44 (0)20 7594 3794 Fax: +44 (0)20 7706 3272 email: (until 9/12/02)

New e-mail: (active from now)



full text ;

AND the new findings of BASE in cattle in Italy of Identification of a
second bovine amyloidotic spongiform encephalopathy: Molecular
similarities with sporadic

Creutzfeldt-Jakob disease

Adaptation of the bovine spongiform encephalopathy agent to primates
and comparison with Creutzfeldt- Jakob disease: Implications for
human health

THE findings from Corinne Ida Lasmézas*, [dagger] , Jean-Guy Fournier*,
Virginie Nouvel*,

Hermann Boe*, Domíníque Marcé*, François Lamoury*, Nicolas Kopp [Dagger

] , Jean-Jacques Hauw§, James Ironside¶, Moira Bruce [||] , Dominique

Dormont*, and Jean-Philippe Deslys* et al, that The agent responsible
for French iatrogenic growth hormone-linked CJD taken as a control is
very different from vCJD but is similar to that found in one case of
sporadic CJD and one sheep scrapie isolate;

Characterization of two distinct prion strains
derived from bovine spongiform encephalopathy
transmissions to inbred mice

ALL animals for human/animal consumption must be tested for TSE.

ALL human TSEs must be made reportable Nationally and Internationally, OF ALL AGES...TSS

P.S. cjd voice et al, we need to get to these families before the foundation does, so we can tell them the whole story, and maybe start issuing a WRITTEN CJD QUESTIONNAIRE to new members, then we must figure out where we can send them. this is the only way we will know the outcome of the verbal cjd questionnaires they are submitting. well, we will never know the outcome of there verbal OVER THE PHONE ONLY cjd questionnaire, but if we start issuing our own as new members come forward, then we will have our own data base to go too and in the future, we can work from that. this BSe about the cost of a cjd questionnaire is total crap. they spend more money than that wining and dining themselves at these conferences and such around the country patting one another on the backs. for goodness sake, we could even do an electronic cjd questionnaire as i tried to do in the past. but we must have an official place to document this data at. until the cjd foundation changes there policy and starts working with us, as opposed to against us, well first they must accept us. they have not done that yet, its plain to see on the front page of the CJD Foundation INC site. some of us are discussing this offline (for various reasons), and trying to figure out a system. everyone i am speaking to says this is the best thing, but it will be difficult. we must stick together......

kindest regards,

#################### ####################


(where you can speak your mind and get some answers)

REFUSE ALL OVER THE PHONE ONLY CJD QUESTIONNAIRES from anyone. DEMAND THE CJD QUESTIONNAIRE BE IN WRITING WITH COPY GOING TO FAMILY! nothing less is acceptable. WE cannot let the federal gov hide and conceal this data like they do data on BSE mad cow cases. IF we do, we will never get any answers to our questions about our loved ones...TSS




Follow Ups:

Post a Followup

E-mail: (optional)


Optional Link URL:
Link Title:
Optional Image URL: