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From: TSS (pool143-247.dial-u2.hou.wt.net)
Subject: DETECTION OF THE BOVINE SPONGIFORM ENCEPHALOPATHY AGENT IN THE CAPRINE SPECIES IN FRANCE Confirmation (final report) OIE
Date: February 4, 2005 at 9:36 am PST

-------- Original Message --------
Subject: DETECTION OF THE BOVINE SPONGIFORM ENCEPHALOPATHY AGENT IN THE CAPRINE SPECIES IN FRANCE Confirmation (final report) OIE
Date: Fri, 04 Feb 2005 11:40:26 -0600
From: "Terry S. Singeltary Sr."
To: Bovine Spongiform Encephalopathy
CC: cjdvoice@yahoogroups.com, i.schuett-abraham@BFR.BUND.DE

DETECTION OF THE BOVINE SPONGIFORM ENCEPHALOPATHY AGENT IN THE CAPRINE
SPECIES IN FRANCE
Confirmation (final report)

See also: 19 November 2004

See Disease Information, 17 (47), 343, dated 19 November 2004

Translation of information received on 4 February 2005 from Dr Isabelle
Chmitelin, Delegate of France to the OIE:

Report date: 1 February 2005.

Reason for immediate notification: evidence of a change in the
epidemiology of a listed disease.

Precise identification of agent: pathological prion protein responsible
for bovine spongiform encephalopathy (BSE).

Date of confirmation of the event: 28 January 2005.

Date of start of the event: 19 November 2002.

Clinical disease: no.

Nature of diagnosis: laboratory.

Details of outbreak:

First administrative division Lower administrative division Type of
epide-miolo-gical unit Name of the location Date of start of the
outbreak Spe-cies Number of animals in the outbreak
susceptible cases deaths destroyed slaugh-tered
Rhône-Alpes region Ardèche department farm Plats 19 Nov. 2002 cap 580 1
0 580 0

Description of affected population: one caprine BSE case was detected in
a dairy goat herd with approximately 300 adult animals.

Diagnosis:

Laboratories where diagnosis was made Species examined Diagnostic tests
used Date Results
AFSSA(1), Lyon cap

- western blot,

- bioassay,

11 Jan. 2005 positive
CEA(2), Saclay and Fontenay-aux-Roses cap

- western blot,

- western blot, - ELISA(4).

11 Jan. 2005 positive
INRA(3), Tours and Jouy-en-Josas cap

- western blot,

- bioassay,

11 Jan. 2005 positive
Veterinary Schools, Toulouse and Paris cap

- western blot,

- bioassay,

11 Jan. 2005 positive

The case was confirmed on 28 January 2005 by VLA Weybridge(5), European
Union Reference Laboratory for Transmissible Spongiform Encephalopathies
and OIE Reference Laboratory for BSE.

Origin of infection: unknown or inconclusive.

Control measure applied: stamping out.

(1) AFSSA: Agence française de sécurité sanitaire des aliments (French
Agency for Food Safety)

(2) CEA: Commissariat à l'énergie atomique (French Atomic Energy Agency)

(3) INRA: Institut national de la recherche agronomique (French National
Institute for Agricultural Research)

(4) ELISA: enzyme-linked immunosorbent assay

(5) Veterinary Laboratories Agency, Weybridge, New Haw, United Kingdom

Note by the OIE Animal Health Information Department: the report from
the Reference Laboratory is available on the internet, at the following
address:
http://europa.eu.int/comm/food/food/biosafety/bse/crl_statement_tse_goats_28-01-05_en.pdf

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http://www.oie.int/eng/info/hebdo/a_current.htm#Sec3

TSS

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