To: BSE-L@LISTSERV.KALIV.UNI-KARLSRUHE.DE
##################### Bovine Spongiform Encephalopathy #####################
Research Project: Bse Pathogenesis Study
Location:
Virus
and Prion Diseases of Livestock
Project Number: 3625-32000-073-06
Project Type: Specific C/A
Start Date: Sep 01, 2004
End Date: Aug 31, 2007
Objective:
The objective of this cooperative research project is to obtain material
from an oral bovine spongiform encephalopathy (BSE) pathogenesis study
performed at the Veterinary Laboratories Agency (VLA)-Weybridge in the
United Kingdom. These BSE materials will be used to identify PrPd tissue
distribution and migration in BSE infected cattle.
Approach:
We will obtain various materials from the bovine spongiform
encephalophathy (BSE) oral pathogenesis study. These materials will be
used to identify PrPd tissue distribution and migration employing
validated and non-validated PrPd detecting methods developed at the NADC
for use with CWD and scrapie. At necropsy, approximately 80 samples were
taken from the animals at various time points post infection. This study
also included ante mortem sampling of body fluids like blood,
cerebrospinal fluid, urine, saliva, nasal secretions, feces and milk at
determined intervals.
http://www.ars.usda.gov/research/projects/projects.htm?ACCN_NO=408830
TSS
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