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From: TSS (216-119-132-46.ipset12.wt.net)
Subject: Eighth case of vCJD identified in France had been a blood donor
Date: October 28, 2004 at 10:33 am PST


-------- Original Message --------
Subject: Eighth case of vCJD identified in France had been a blood donor
Date: Thu, 28 Oct 2004 12:40:23 -0500
From: "Terry S. Singeltary Sr."
Reply-To: Bovine Spongiform Encephalopathy
To: BSE-L@UNI-KARLSRUHE.DE


##################### Bovine Spongiform Encephalopathy #####################

Eighth case of vCJD identified in France had been a blood donor

Editorial team (eurosurveillance.weekly@hpa.org.uk
), Eurosurveillance editorial
office

Another case of variant Creutzfeldt-Jakob disease has been identified by
the surveillance system set up by the Institut de Veille Sanitaire and
the National Institute of Health and Medical Research (INSERM) in
France. This is the eighth case to have been identified in France since
1996.

The patient is known to have donated blood on several occasions between
1993 and 2003. These donations were used to supply red blood cells for
transfusion, and also for the manufacture of blood products. None of the
seven previous French vCJD patients had, to the knowledge of their
families and the National Blood Service, donated blood.

The risk of vCJD transmission by transfusion has been informed by recent
reports from the UK [2,3]. The ten people who have received transfusions
(red blood cells) donated by this donor/vCJD patient are being informed
by their doctor of their risk and any actions they should take.

The risk of vCJD transmission by plasma-derived products has not been
established, and if it exists, may be reduced by various stages of
fractionation. The French Laboratory of Fractionation and
Biotechnologies has identified the product batches in which the plasma
from this vCJD case was used. Distribution of these batches has been
stopped and a recall of products in stock is being issued.

The risk of transmission of vCJD by blood products has been evaluated
several times by the French Agency for Safety of Health products
(lAgence française de sécurité sanitaire des produits de santé,
AFSSAPS), most recently in February 2004.

The risks to the individuals who have received blood products of the
implicated batches will be assessed by an expert group convened by the
AFSSAPS, with consideration of the nature of the product and the
quantities received.

This article was translated and adapted from reference 1 by the
Eurosurveillance editorial team

References:

1. Ministère de la santé et de la Protection sociale. Maladie de
Creutzfeldt-Jakob : un huitième cas de nouveau variant. Press
release. 21 October 2004.
(http://www.sante.gouv.fr/htm/actu/31_041021.htm)
2. Possible second case of variant CJD prion protein transmission
from blood transfusion in the UK. Eurosurveillance Weekly 2004:
8(31): 29/07/2004
(http://www.eurosurveillance.org/ew/2004/040729.asp#2)
3. CDR editorial team. Possible case of transfusion-associated
variant CJD in the United Kingdom. Eurosurveillance Weekly 2003;
7(51): 18/12/2004
(http://www.eurosurveillance.org/ew/2003/031218.asp#2)

http://www.eurosurveillance.org/ew/2004/041028.asp

tss

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