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From: TSS (216-119-138-199.ipset18.wt.net)
Subject: Epidemiological Study of Creutzfeldt-Jakob Disease Death Certificates in Canada, 1979-2001
Date: October 6, 2004 at 11:19 am PST

-------- Original Message --------
Subject: Epidemiological Study of Creutzfeldt-Jakob Disease Death Certificates in Canada, 1979-2001
Date: Wed, 06 Oct 2004 13:17:31 -0500
From: "Terry S. Singeltary Sr."
To: Bovine Spongiform Encephalopathy
CC: cjdvoice@yahoogroups.com


Original Paper

Epidemiological Study of Creutzfeldt-Jakob Disease Death Certificates in
Canada, 1979-2001
Susie ElSaadanya, Robert Semenciwc, Maura Rickettsb, Yang Maoc, Antonio
Giulivib

aStatistics and Risk Assessment Section,
bBlood Safety Surveillance and Health-Care Acquired Infections Division,
Centre for Infectious Disease Prevention and Control,
cSurveillance and Risk Assessment Division, Centre for Chronic Disease
Prevention and Control, Population and Public Health Branch, Health
Canada, Ottawa, Canada

Address of Corresponding Author


Neuroepidemiology 2005;24:15-21 (DOI: 10.1159/000081044)

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Key
Words

* Creutzfeldt-Jakob disease
* Death certificate
* Epidemiology

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Abstract

Introduction: A descriptive epidemiological analysis to update trends of
Creutzfeldt-Jakob disease (CJD) deaths, from 1979-2001, was undertaken.
Methods: Cases with CJD as underlying cause were extracted. Age-adjusted
death rates by age, sex, and province were calculated. Information on
birthplace, autopsy indications and type of work were examined for death
certificates from 1979 to 1997. Results: 462 cases were identified
between 1979 and 1997. The average annual age-standardized mortality
rate was 0.93 deaths per million persons during this period and 1.03 for
1998-2001. Persons 60 years or older demonstrated the highest average
annual mortality rate. Rates were slightly higher among males and
increased with age. Persons born in Canada accounted for 72% of deaths.
Cause of death was verified by autopsy for 9.1% of patients while 21% of
deaths indicated that additional information relating to underlying
cause was expected. The service industry occupation represented the
largest mortality (Quebec does not capture these data). Conclusions:
Canadian rates are consistent with those of the United States and
slightly higher than those of certain European countries. Approximately
44% of CJD cases had an autopsy record, though many were incomplete. We
are unable to determine a relation with occupation. We recommend annual
analysis of CJD death registrations for updated surveillance of trends,
as mortality data are an efficient tool for monitoring incidence.

Copyright © 2005 S. Karger AG, Basel

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Author
Contacts

Susie ElSaadany, Chief, Statistics and Risk Assessment Section, Blood
Safety Surveillance
and Health-Care Acquired Infections Div., Ctr. for Infectious Disease
Prevention and
Control, Population and Public Health Branch, Health Canada, A.L. 0601E2
Health Canada Bldg. 6, Tunney's Pasture, Ottawa, Ont. K1A 0L2 (Canada)
Tel. +1 613 952 6925, Fax +1 613 952 6668, E-Mail
susie_elsaadany@hc-sc.gc.ca

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Article
Information

Published online: September 23, 2004
Number of Print Pages : 7
Number of Figures : 3, Number of Tables : 3, Number of References : 42

http://content.karger.com/produktedb/produkte.asp?typ=fulltext&file=NED20050241_2015#AC

TSS





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