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From: TSS (216-119-133-141.ipset13.wt.net)
In Reply to: Bio-Rad's Second Generation CWD Test Approved by USDA (STILL REFUSING TO RAPID TSE TEST CATTLE) posted by TSS on July 16, 2003 at 6:20 am:
-------- Original Message -------- Hi Terry Careful, when you obtain your information from a TSE congress sponsored The Bio-Rad test is not the fastest test, the test of Enfer as well as The US is currently doing all their BSE checks with the classical It has to be noted, however, that a good surveillance system can also be Regards Markus Moser -----Original Message----- At a TSE meeting sponsored by Bio-Rad last year I overheard that the reagents used in the to Bio-Rad tests for CWD are the same as those used in the BSE test in Europe. If true, the most rapid and sensitive BSE test is approved for use in the U.S. but the government wants it limited to CWD. Be interesting if someone started testing cows on their own ... http://www.vegsource.com/talk/madcow/messages/788.html MAYBE, someone could elaborate on this please ??? thanks terry http://www.bio-rad.com/B2B/BioRad/br_corp.jsp?BV_SessionID=@@@@191819258 http://www.bio-rad.com/B2B/BioRad/product/br_category.jsp?BV_SessionID=@ Chronic Wasting Disease Click for: | Ordering Information | Transmissible spongiform encephalopathy (TSE) is a slow degenerative disease of the central nervous system thought to be caused by an unconventional agent known as a prion. Prions are abnormally configured proteins in the brain of infected animals and are associated with sponge-like holes in the brain. Abnormal prions also accumulate in the lymph nodes and tonsils of certain animals. TSEs affect bovines in the form of bovine spongiform encephalopathy (BSE), sheep in the form of scrapie, deer and elk in the form of chronic wasting disease (CWD), and humans in the form of a variant of Creutzfeld-Jakob disease (CJD). The problem of CWD in both captive and wild deer and elk populations in the United States has increased dramatically in the past year, with cases being found outside known enzootic areas and in states where it was not present before. The Bio-Rad CWD test combines a purification protocol for increased sensitivity with rapid detection by ELISA. Results are available in 4 hours. The patented purification technique starts with thorough and complete homogenization of the tissue sample. Selective degradation of normal proteins with proteinase K allows improved isolation of the disease-associated abnormal prion. The sample is concentrated for further sensitivity. The ELISA test utilizes two specific monoclonal antibodies, ensuring increased selectivity. A final color change reaction measured by a plate reader ensures accuracy. Over 36,700 samples were analyzed using the Bio-Rad CWD assay in the 2002 hunting season. SNIP... http://www.bio-rad.com/B2B/BioRad/product/br_category.jsp?BV_SessionID=@ TSS Terry S. Singeltary Sr. wrote: > ######## Bovine Spongiform Encephalopathy > ######### > > Bio-Rad's Second Generation CWD Test Approved by USDA > Tuesday July 15, 3:18 pm ET > > New Test Kit Used on Automated Platform Increases Testing Capacity, > Enabling Laboratories to Test Up to 1000 Samples Per Day > > HERCULES, Calif., July 15 /PRNewswire-FirstCall/ -- Bio-Rad > Laboratories, Inc. (Amex: BIO; BIO.B), a multinational manufacturer > distributor of life science research products and clinical diagnostics > announced today that it has received approval from the United States > Department of Agriculture (USDA) to sell its TeSeE(r) test kit, the > company's second generation test kit used for the detection of Chronic > Wasting Disease (CWD) in deer and elk. This CWD test kit is the only > of its kind. It runs on an automated robotics platform that speeds up > sample preparation, enabling laboratories to provide faster results. > Technicians using this new testing platform can process up to 1,000 > samples per day. > > > > > Validation data collected from a study led by Dr. Barbara Powers of > Colorado State University Veterinary Diagnostic Laboratory, Fort > Collins, showed that the test kit performed successfully when compared > to the immunohistochemistry (IHC) test. The benefit of the new Bio-Rad > test is that it offers the same level of sensitivity as the IHC > but more samples can be tested in a shorter amount of time and with > fewer technicians than IHC. The IHC method takes three to five days to > obtain results, whereas the Bio-Rad test can be completed in less than > five hours. > > "We are pleased to be able to provide this new platform to > conducting CWD testing and hope that it will assist them in their > efforts to meet the increasing demand for rapid testing," said Norman > Schwartz, Bio-Rad President and CEO. > > This new CWD test is based on the same proven technology as Bio-Rad's > first generation CWD test, which was approved by the USDA in October > 2002. The test uses the ELISA (enzyme-linked immunosorbent assay) > to detect the abnormal prion protein associated with Chronic Wasting > Disease and is reported to be the fastest and the easiest method to > adapt to mass screening programs. Bio-Rad's first generation CWD test > was used to screen deer and elk samples during the 2002 hunting > > Bio-Rad Laboratories, Inc. (www.bio-rad.com ) > a multinational manufacturer and distributor of life science research > products and clinical diagnostics. It is based in Hercules, > and serves more than 70,000 research and industry customers worldwide > through a network of more than 30 wholly owned subsidiary offices. > > Various statements made within this press release may constitute > "forward-looking statements" for purposes of the Securities and > Commission's "safe harbor" provisions under the Private Securities > Litigation Reform Act of 1995 and Rule 3b-6 under the Securities > Exchange Act of 1934. The forward-looking statements contained herein > involve risks and uncertainties that could cause results to differ > materially from the Company's expectations. > > > > Source: Bio-Rad Laboratories, Inc. > > http://biz.yahoo.com/prnews/030715/sftu107_1.html > > what is wrong with using Bio-Rad or Prionics rapid TSE > test on cattle??? > > why does USDA refuse to approve a rapid test for USA cattle $$$\ > > 1 million BSE/TSE rapid test on USA cattle annually for 5 years ! > > USA BSE/TSE GBR to III ASAP ! > > TSS > > ########### http://mailhost.rz.uni-karlsruhe.de/warc/bse-l.html > ############ > ########### http://mailhost.rz.uni-karlsruhe.de/warc/bse-l.html ############
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