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From: TSS ()
Subject: First results of chronic wasting disease (CWD) surveillance in the South-Eastern part of Belgium
Date: October 27, 2005 at 2:23 pm PST

First results of chronic wasting disease (CWD) surveillance in the South-Eastern part of Belgium

S. Roels, C. Saegerman, H. De Bosschere, D. Berkvens, F. Gregoire, A. Hoyoux, B. Mousset, D. Desmecht, E. Vanopdenbosch and A. Linden
Pages 98-104

Chronic wasting disease (CWD) has not been reported in Europe, whereas it is considered to be enzoo-tic in free-ranging mule deer, Rocky mountain elk and white-tailed deer in the area of Colorado, Wyoming, and Nebraska, and new foci of CWD have been detected in other parts of the United States. However, no large-scale active epidemiosurveillance of European wild cervids has been installed in Europe. In accordance with the opinion of the European Scientific Steering Committee, a preliminary (active) surveillance scheme was installed, in order to improve the knowledge of the CWD status of the Belgian free-ranging cervids (roe deer and red deer). Spleen samples (n=866) of roe deer and red deer collected in the south-eastern part of Belgium, were examined for CWD using a enzyme- linked immunosorbent assay of Bio-Rad. Afterwards, the ELISA was systematically confirmed by immunohistochemistry using three antibodies, namely R524, 2G11 and 12F10. There were no indicati-ons on the occurrence of transmissible spongiform enncephalopathy (TSE) in any of the samples. A Bayesian framework was used for the estimation of the true prevalence of CWD in south-eastern part of Belgium that was estimated to have a median value of zero with a 95% percentile value of 0.00115.



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