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Healthy Lifestyle |
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| VegSource | Back to Discussion Board | Healing Heart Foundation |
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From: Dr. Neal Pinckney (user-10cm74j.cable.mindspring.com)
In Reply to: Re: Safe Statin-Advicor,Garlic Pills posted by James Houston on August 13, 2003 at 11:07 am:
Advicor contains niacin extended-release and lovastatin in combination. The niacin is nicotinic acid, or 3-pyridinecarboxylic acid. Lovastatin is also known by the manufacturer's brand name, Mevacor, a cholesterol lowering agent isolated from a strain of Aspergillus terreus Adverse reactions for Advicor that have been reported by the manufacturer:
Subject: Re: Safe Statin-Advicor,Garlic Pills
Date: August 13, 2003 at 3:28 pm PST
"In controlled clinical studies, 40/214 (19%) of patients randomized to ADVICOR™ discontinued therapy prior to study completion, 18/214 (8%) of discontinuations being due to flushing. In the same controlled studies, 9/94 (10%) of patients randomized to lovastatin and 19/92 (21%) of patients randomized to NIASPAN® also discontinued treatment prior to study completion secondary to adverse events. Flushing episodes (i.e., warmth, redness, itching and/or tingling) were the most common treatment-emergent adverse events, and occurred in 53% to 83% of patients treated with ADVICOR™. Spontaneous reports with NIASPAN® and clinical studies with ADVICOR™ suggest that flushing may also be accompanied by symptoms of dizziness or syncope, tachycardia, palpitations, shortness of breath, sweating, chills, and/or edema."
Anything one does to help lower cholesterol is helpful, but even large amounts of garlic don't typically lower it significantly. For most people, the best course is to lower all fat intake, totally avoid any saturated and hydrogenated fats, and exercise regularly.
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