From a Dr. and Biochemist perspective, There are several forms of B-12
The traditional one, which is the cheapest for companies to acquire and sell is
cyanocobalamin, and it does has side effects.
It is contaminated with poisonous cyanide during its chemical extraction from animal tissues. Hence the name.
You want a methyl donor, thus ONLY buy B-12 in the form of Methylcobalamin
Methylcobalamin has "metabolic and therapeutic" applications according to Dr. Sahelian. He notes methylcobalamin helps in the formation of S-adenosylmethionine (SAM-e), a popular mood-altering compound. Chronic Fatigue Syndrome and Fibromyalgia patients have also reported an increase in health with the use of B-12.
of course pharmacies sell junk. LEF.org, mercola.com and vitacost.com is my preference for buying quality with value, the NSI brand. Why take Vitamin D2 and make your body convert it to D3, why take B12 as cyanocobalimin and make your body convert it it. Plus, you want a Methyl donor.
Just like you want sulfates.... Thus Glucosamine Hydroxide is junk, while Glucosamine Sulfate is what u want. MSM is Methylsulfonylmethane. Taken at 4,000 per day it is effective.
I notice NOTHING with garbage B-complex sold by the masses. When i take a B-complex from Vitacost.com 3 times a day, i don't need caffeine at all.
best of health.
Kidneys are NOT detected as impaired unless the nephrons are only working below 20% , less why in the world take your chances. Stop buying the Walmart and other store junk. You are not saving any money, spending more.... for garbage vitamins.
Plus, you need HCL to absorb your vitamins. If you on on a acid blocker, you are not going to absorb much. You really want to take apple cider vinegar with your vitamins.
Posted by tazman, March 8, 2014 at 01:24 PM
Posted by tazman, March 8, 2014 at 09:08 AM
Posted by tazman, March 6, 2014 at 05:00 AM
Posted by tazman, March 4, 2014 at 11:25 AM
Happily, regular use of sublingual tablets has been shown to be as effective at bringing levels up into the optimal zone. We take 1000 mcg every other day, dissolved under the tongue.
In response to an article published on Naturalnews.com denying the possibility of B12 deficiency for vegans, American dietician Jack Norris RD kindly prepared the following:
quoted from: http://jacknorrisrd.com/?p=1284
On Saturday, August 21, NaturalNews.com published an article by Cindy Jones-Shoeman, Vegan Vitamin B12 Deficiency is a Myth.
The article starts out by saying that “nothing could be further from the truth” than the idea that vegans can suffer a B12 deficiency from their diet.
The article by Jones-Shoeman appears to be a rehashing of an old article (apparently from 2004 or earlier) by Vivian Vetrano, “Rethinking & Clarifying the Vitamin B12 Issue” which appears on the Rest of Your Life Retreat website: roylretreat.com/articles/b12.html.
Although Vetrano’s article is one of the most fanciful stories I’ve ever read about vitamin B12, it is rather detailed and I will only respond to the excerpts from the Jones-Shoeman article:
“According to Dr. Vivian V. Vetrano, vitamin B12 actually comes from coenzymes, which are already present in bacteria found on the human body (in and around the mouth, for example).”
Vitamin B12 does not come from co-enzymes, it is a co-enzyme. Bacteria do produce vitamin B12, but there is no proof that bacteria living in most people’s mouths produce active vitamin B12 or produce it in amounts large enough that it could prevent B12 deficiency. This is underlined by the fact that many vegans develop full-blown vitamin B12 deficiency, and in some cases permanent neurological damage, as can be seen here: VeganHealth.org/b12/cases. In addition to those cases in the scientific journals, I have known many people who have suffered from B12 deficiency and cured it by supplementing with cyanocobalamin (the most stable form of vitamin B12).
About a dozen studies have correlated low vitamin B12 levels in vegans with elevated homocysteine levels. Elevated homocysteine levels have been linked to early death, primarily from cardiovascular disease, and Alzheimer’s Disease. More details on that are at VeganHealth.org/b12/hcy.
“In fact, vitamin B12 deficiency is often, according to Dr. Vetrano, a symptom of a larger problem; that is, it’s not caused from a poor diet but rather from deficiency diseases…”
While it is true that about 2% of the population has trouble absorbing vitamin B12, the vast majority of problems that have been seen in vegans have been caused by a low B12 intake, not from absorption problems.
“Vitamin B12 deficiency due to a vegan diet is simply a lie that finally needs to be put to rest.”
Unfortunately, this could not be further from the truth. The most common, serious damage that results from vitamin B12 deficiency is when a pregnant vegan who does not supplement has a baby who also does not get any B12 supplementation. Typically, around 6 months of age, the infant’s growth and neurological development ceases and then begins to regress. In many cases, such infants have sustained permanent brain damage.
Vitamin B12 deficiency among vegans is real and is not something to be flippant about. It is so important that a number of vegan health professionals and organizations have endorsed an open letter to the vegan community, What Every Vegan Should Know about Vitamin B12 (VeganHealth.org/articles/everyvegan). This letter has been signed by The Vegan Society (UK), Vegan Outreach, and many members of the International Vegetarian Union science group.
While we will agree that the methyl form is better, it can also be harder to find. Most pharmacies carry the cyano form since it is cheaper and more stable.
Thankfully, concern about cyanide from a cyanocobalamin supplement really only applies to people with compromised kidney function. See this website for more detail: http://www.veganhealth.org/b12/nocyano
Quote: "While being a natural chemical produced in the body, cyanide is toxic, and the body turns it into thiocyanate in order to excrete it. If this pathway is defective or overwhelmed through ingestion of too much cyanide (such as in smokers, or people in Nigeria who eat large amounts of cassava which is high in cyanide)... a different form of B12 should be given... "
So when the methyl form is available, great! However, for those of us who are non-smokers, rarely eat cassava, and have a healthy detoxification system, taking the cyano form is still a whole lot better than not taking any B12.
Jack Norris RD has responded directly to the comments made by Doug Graham, here:
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